HCID 16770985, compound → HCID 21506103, compound

HRID 918610Notes

Reaction equation

HRID 918610 reaction equation
[CH3:1][O:2][C:3]1[C:11]([S:12](=[O:15])(=[O:14])[NH2:13])=[CH:10][C:6]([C:7]([OH:9])=[O:8])=[CH:5][C:4]=1[N+:16]([O-])=O>C(=O)([O-])O.[Na+]>[NH2:16][C:4]1[CH:5]=[C:6]([CH:10]=[C:11]([S:12](=[O:15])(=[O:14])[NH2:13])[C:3]=1[O:2][CH3:1])[C:7]([OH:9])=[O:8]

Participants

3

Reactant 1

HCID 16770985HCID 16770985, compound

Product 1

HCID 21506103HCID 21506103, compound

Reagents, catalysts & solvents 1

HCID 516892Sodium BicarbonateSolvent

Procedure

4-Methoxy-3-nitro-5-sulphamyl-benzoic acid (2.8 g) was dissolved in 1N sodium hydrogen carbonate solution (12 ml), and hydrogenated, using Pd-on-carbon as a catalyst, and the 3-amino-4-methoxy-5-sulphamyl-benzoic acid was isolated as described in Example 1 B. After several recrystallizations from water and drying at 78°C in vacuo, the melting point was 210°C under decomposition.

Sources & evidence

ORD record
ord-b7b6b0a1de034801b0c8599cc4ea0bcc
Source dataset
uspto-grants-1976_07
Patent number
US03971819

Reaction notes

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