Hydrochloric Acid → 4-Anilino-3-nitro-5-sulphamyl-benzoic acid

HRID 918611노트

반응식

HRID 918611 반응식
Cl[C:2]1[C:10]([S:11](=[O:14])(=[O:13])[NH2:12])=[CH:9][C:5]([C:6]([OH:8])=[O:7])=[CH:4][C:3]=1[N+:15]([O-:17])=[O:16].[NH2:18][C:19]1[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=1.Cl>O>[NH:18]([C:2]1[C:10]([S:11](=[O:14])(=[O:13])[NH2:12])=[CH:9][C:5]([C:6]([OH:8])=[O:7])=[CH:4][C:3]=1[N+:15]([O-:17])=[O:16])[C:19]1[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=1

참가 물질

5

반응물 3

HCID 313Hydrochloric AcidHCID 6115AnilineHCID 898934-Chloro-3-nitro-5-sulphamoylbenzoic acid

생성물 1

HCID 215060714-Anilino-3-nitro-5-sulphamyl-benzoic acid

시약·촉매·용매 1

HCID 962Water용매

반응 조건

온도
80 °C

실험 절차

A mixture of 4-chloro-3-nitro-5-sulphamyl-benzoic acid (8.4 g), aniline (8.4 g), and water (40 ml) was stirred at 80°C for 2 hours. After the addition of 1N hydrochloric acid (50 ml) and cooling, the precipitated 4-anilino-3-nitro-5-sulphamyl-benzoic acid was collected by suction, washed with water, and recrystallized from aqueous ethanol. The melting point was 261°-262°C.

후처리

  1. temperaturecooling
  2. customthe precipitated 4-anilino-3-nitro-5-sulphamyl-benzoic acid was collected by suction
  3. washwashed with water
  4. customrecrystallized from aqueous ethanol

출처 및 근거

ORD 기록
ord-202e0f6180074915853a15bdc90a0a27
출처 데이터셋
uspto-grants-1976_07
특허 번호
US03971819

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