Hydrochloric Acid → HCID 21506045, compound

Participants

Reaction Steps

Ethyl-4-(2-methyl-6-pyridylamino)-3-nitro-5-sulphamyl-benzoate (2 g) was dissolved in 1N sodium hydroxide (30 ml) and heated on a steam bath for 1 hour. After cooling, water (50 ml) was added, and the pH of the reaction mixture was adjusted to 4.5 by addition of 1N hydrochloric acid. The precipitated 4-(2-methyl-6-pyridylamino)-3-nitro-5-sulphamyl-benzoic acid was collected by suction, washed with water, and dried. The compound had a melting point of 305°C (decomp.).

Provenance & Evidence