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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 918828Generated: November 1, 2026

2-Fluoro-5-(trifluoromethoxy)benzylamine → 6-Bromo-N-(2-fluoro-5-(trifluoromethoxy)benzyl)imidazo[1,2-a]pyridine-2-carboxamide

https://huagongshe.com/reaction/918828

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Fluoro-5-(trifluoromethoxy)benzylamineHCID 3739302—
ReactantEthyl 6-bromoimidazo[1,2-a]pyridine-2-carboxylateHCID 7141939—
Product6-Bromo-N-(2-fluoro-5-(trifluoromethoxy)benzyl)imidazo[1,2-a]pyridine-2-carboxamideHCID 118113947—

Reaction Steps

The title compound was prepared by essentially following the same procedures described for Intermediate I, using (2-fluoro-5-(trifluoromethoxy)phenyl)methanamine and ethyl 6-bromoimidazo[1,2-a]pyridine-2-carboxylate as starting materials.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09271969B2
Source datasetuspto-grants-2016_03
ORD IDord-32e750e570a842d290e83e223bce9667
Source noteuspto-grants-2016_03