Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 918860Generated: November 2, 2026

Ethyl 6-bromoimidazo[1,2-a]pyridine-2-carboxylate → 6-Bromo-N-(4-chloro-2,6-difluorobenzyl)imidazo[1,2-a]pyridine-2-carboxamide

https://huagongshe.com/reaction/918860

Reaction equation

Participants

RoleNameHCIDCharge
ReactantEthyl 6-bromoimidazo[1,2-a]pyridine-2-carboxylateHCID 7141939—
Reactant(4-Chloro-2,6-difluorophenyl)methanamineHCID 17750831—
Product6-Bromo-N-(4-chloro-2,6-difluorobenzyl)imidazo[1,2-a]pyridine-2-carboxamideHCID 118113883—

Reaction Steps

The title compound was prepared by using procedures analogous to those described for the synthesis of Intermediate I, using (4-chloro-2,6-difluorophenyl)methanamine and ethyl 6-bromoimidazo[1,2-a]pyridine-2-carboxylate as starting materials.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09271969B2
Source datasetuspto-grants-2016_03
ORD IDord-16fa3bd2bd84463596acdedc6ca89ecd
Source noteuspto-grants-2016_03