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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 918866Generated: November 2, 2026

2-Bromoimidazo[2,1-b]thiazole-6-carboxylic acid → 2-Bromo-N-(3-chloro-4-(trifluoromethoxy)benzyl)imidazo[2,1-b]thiazole-6-carboxamide

https://huagongshe.com/reaction/918866

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Bromoimidazo[2,1-b]thiazole-6-carboxylic acidHCID 12744615—
Reactant(3-Chloro-4-(trifluoromethoxy)phenyl)methanamineHCID 53414455—
Product2-Bromo-N-(3-chloro-4-(trifluoromethoxy)benzyl)imidazo[2,1-b]thiazole-6-carboxamideHCID 118113901—

Reaction Steps

The title compound was prepared by essentially following the same procedures described for Intermediate XLVI, using (3-chloro-4-(trifluoromethoxy)phenyl)methanamine and 2-bromoimidazo[2,1-b]thiazole-6-carboxylic acid as starting materials.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09271969B2
Source datasetuspto-grants-2016_03
ORD IDord-9ce2e8e86d5542aeb6850d95ab1b5cd8
Source noteuspto-grants-2016_03