4-Hydroxyphenylboronic acid → HCID 67963768, compound

HRID 919043Notes

Reaction equation

HRID 919043 reaction equation
[C:1]1([C@H:7]([O:9][C:10](=[O:19])[NH:11][C:12]2[CH:17]=[CH:16][CH:15]=[CH:14][C:13]=2Br)[CH3:8])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[OH:20][C:21]1[CH:26]=[CH:25][C:24](B(O)O)=[CH:23][CH:22]=1>>[C:1]1([C@H:7]([O:9][C:10](=[O:19])[NH:11][C:12]2[CH:17]=[CH:16][CH:15]=[CH:14][C:13]=2[C:24]2[CH:25]=[CH:26][C:21]([OH:20])=[CH:22][CH:23]=2)[CH3:8])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1

Participants

3

Reactant 2

HCID 27343604-Hydroxyphenylboronic acidHCID 67963770HCID 67963770, compound

Product 1

HCID 67963768HCID 67963768, compound

Procedure

Prepared according to the procedure described in Example 1, Step 2, using the following starting materials: (2-bromo-phenyl)-carbamic acid (R)-1-phenyl-ethyl ester and 4-hydroxyphenylboronic acid.

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-859b612371354d1da3649e4860ed028c
Source dataset
uspto-grants-2016_03
Patent number
US09272990B2

Reaction notes

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