HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-(4-Boronophenyl)cyclopropane-1-carboxylic acid → 1-{4'-[3-((R)-1-Phenyl-ethoxycarbonylamino)-pyridin-4-yl]-biphenyl-4-yl}-cyclopropanecarboxylic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-(4-Boronophenyl)cyclopropane-1-carboxylic acid | HCID 46739666 | — |
| Reactant | trifluoro-methanesulfonic acid 4-[3-((R)-1-phenyl-ethoxycarbonylamino)-pyridin-4-yl]-phenyl ester | HCID 86697087 | — |
| Product | 1-{4'-[3-((R)-1-Phenyl-ethoxycarbonylamino)-pyridin-4-yl]-biphenyl-4-yl}-cyclopropanecarboxylic acid | HCID 57386116 | — |
Reaction Steps
Prepared according to the procedure described in Example 1, Step 2, using the following starting materials: trifluoro-methanesulfonic acid 4-[3-((R)-1-phenyl-ethoxycarbonylamino)-pyridin-4-yl]-phenyl ester and 1-(4-boronophenyl)cyclopropanecarboxylic acid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09272990B2 |
| Source dataset | uspto-grants-2016_03 |
| ORD ID | ord-6ba083e555d04965b49d59894e483148 |
| Source note | uspto-grants-2016_03 |