反应详情

[1-(4-Bromo-phenyl)-cyclopropyl]-acetonitrile (from previous step) was dissolved in EtOH (50 mL) and H2O (6 mL). Potassium hydroxide (5.4 g, 96 mmol) was added and the reaction was heated to reflux overnight. After cooling the reaction was submitted to standard aqueous workup and purified on silica gel to yield the title compound.

1. temperaturethe reaction was heated
2. temperatureto reflux overnight
3. temperatureAfter cooling the reaction
4. custompurified on silica gel