HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-(3-Bromo-thiophen-2-yl)-4-phenyl-butan-1-ol → (1-{4'-[2-(1-Hydroxy-4-phenyl-butyl)-thiophen-3-yl]-biphenyl-4-yl}-cyclopropyl)-acetic acid ethyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-(3-Bromo-thiophen-2-yl)-4-phenyl-butan-1-ol | HCID 67963765 | — |
| Reactant | {1-[4'-(4,4,5,5-Tetramethyl-[1,3,2]dioxaborolan-2-yl)-biphenyl-4-yl]-cyclopropyl}-acetic acid ethyl ester | HCID 67963776 | — |
| Product | (1-{4'-[2-(1-Hydroxy-4-phenyl-butyl)-thiophen-3-yl]-biphenyl-4-yl}-cyclopropyl)-acetic acid ethyl ester | HCID 67958069 | — |
Reaction Steps
Prepared according to the procedure described in Example 1, Step 2, using the following starting materials: 1-(3-bromo-thiophen-2-yl)-4-phenyl-butan-1-ol and {1-[4′-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-biphenyl-4-yl]-cyclopropyl}-acetic acid ethyl ester.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09272990B2 |
| Source dataset | uspto-grants-2016_03 |
| ORD ID | ord-0ae324e2401e42528ee25fc2c6de38d5 |
| Source note | uspto-grants-2016_03 |