HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-[3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]-1H-pyrazole → 2-Amino-5-(3-pyrazol-1-yl-phenyl)-N-pyridazin-4-yl-nicotinamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-[3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]-1H-pyrazole | HCID 4961249 | — |
| Reactant | 2-amino-5-bromo-N-pyridazin-4-yl-nicotinamide | HCID 71061471 | — |
| Product | 2-Amino-5-(3-pyrazol-1-yl-phenyl)-N-pyridazin-4-yl-nicotinamide | HCID 71061062 | — |
Reaction Steps
Reaction of 2-amino-5-bromo-N-pyridazin-4-yl-nicotinamide (see step 1 in the synthesis of “A16”) and 1-[3-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-phenyl]-1H-pyrazole gives the compound “A18”;
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09273029B2 |
| Source dataset | uspto-grants-2016_03 |
| ORD ID | ord-bf5a1c3704db4471919b9719c888f9e8 |
| Source note | uspto-grants-2016_03 |