HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl]acetamide → 2-Amino-5-(1-carbamoylmethyl-1H-pyrazol-4-yl)-N-pyridin-4-yl-nicotinamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl]acetamide | HCID 56965734 | — |
| Reactant | 2-amino-5-bromo-N-(pyridin-4-yl)nicotinamide | HCID 62155416 | — |
| Product | 2-Amino-5-(1-carbamoylmethyl-1H-pyrazol-4-yl)-N-pyridin-4-yl-nicotinamide | HCID 71060849 | — |
Reaction Steps
Reaction of 2-amino-5-bromo-N-pyridin-4-yl-nicotinamide with 2-[4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-pyrazol-1-yl]-acetamide gives the compound “A25”; HPLC/MS: 0.94 min, [M+H]=338;
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09273029B2 |
| Source dataset | uspto-grants-2016_03 |
| ORD ID | ord-cc4ce857b1424381ac711e33b0b06fec |
| Source note | uspto-grants-2016_03 |