HuagongsheHuagongshe Chemistry Print Report · For research reference only
1,2-Ethanediamine, N1,N1,N2-trimethyl- → 2-Amino-5-{4-[(2-dimethylamino-ethyl)-methyl-carbamoyl]-phenyl}-N-pyridin-4-yl-nicotinamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1,2-Ethanediamine, N1,N1,N2-trimethyl- | HCID 67338 | — |
| Reactant | 4-[6-Amino-5-(pyridin-4-ylcarbamoyl)-pyridin-3-yl]-benzoic acid | HCID 71061416 | — |
| Product | 2-Amino-5-{4-[(2-dimethylamino-ethyl)-methyl-carbamoyl]-phenyl}-N-pyridin-4-yl-nicotinamide | HCID 71080402 | — |
Reaction Steps
Reaction of 4-[6-amino-5-(pyridin-4-ylcarbamoyl)-pyridin-3-yl]-benzoic acid with N,N,N′-trimethylethylenediamine gives “A90”; method 2: HPLC/MS: 1.55 min, [M+H]419;
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09273029B2 |
| Source dataset | uspto-grants-2016_03 |
| ORD ID | ord-a04941c203994bcd867ef0f6fc1fcf4d |
| Source note | uspto-grants-2016_03 |