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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 919649Generated: November 1, 2026

Trifluoroacetic acid → 1374251-00-9

https://huagongshe.com/reaction/919649

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTrifluoroacetic acidHCID 6422—
ReactantHCID 67517324HCID 67517324—
SolventDichloromethaneHCID 6344—
Product1374251-00-9HCID 67517602129.1%

Reaction Steps

To the solution of tert-butyl 3-(4-amino-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidine-1-carboxylate (700 mg, 2.2 mmol) in CH2Cl2 (10 mL) was added TFA (2 mL). The resulting mixture was stirred at rt for 1 h, and concentrated in vacuo to afford the title compound (620 mg, 100%) which was used without further purification. ESI-MS (M+H′): 219.0.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09273028B2
Source datasetuspto-grants-2016_03
ORD IDord-6465ce7c41184295a3f0b21adbb27d29
Source noteuspto-grants-2016_03