HuagongsheHuagongshe Chemistry Print Report · For research reference only
Trifluoroacetic acid → 1374251-00-9
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Trifluoroacetic acid | HCID 6422 | — |
| Reactant | HCID 67517324 | HCID 67517324 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | 1374251-00-9 | HCID 67517602 | 129.1% |
Reaction Steps
To the solution of tert-butyl 3-(4-amino-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidine-1-carboxylate (700 mg, 2.2 mmol) in CH2Cl2 (10 mL) was added TFA (2 mL). The resulting mixture was stirred at rt for 1 h, and concentrated in vacuo to afford the title compound (620 mg, 100%) which was used without further purification. ESI-MS (M+H′): 219.0.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09273028B2 |
| Source dataset | uspto-grants-2016_03 |
| ORD ID | ord-6465ce7c41184295a3f0b21adbb27d29 |
| Source note | uspto-grants-2016_03 |