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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 920375Generated: October 25, 2026

4-Chloro-3-(trifluoromethyl)benzyl alcohol → 8-((4-chloro-3-(trifluoromethyl)benzyl)oxy)-1-methyl-3,4-dihydro-1H-pyrimido[1,6-a]pyrimidin-6(2H)-one

https://huagongshe.com/reaction/920375

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Chloro-3-(trifluoromethyl)benzyl alcoholHCID 2778111—
Reactant8-Chloro-1-methyl-3,4-dihydro-1H-pyrimido[1,6-A]pyrimidin-6(2H)-oneHCID 71743471—
Product8-((4-chloro-3-(trifluoromethyl)benzyl)oxy)-1-methyl-3,4-dihydro-1H-pyrimido[1,6-a]pyrimidin-6(2H)-oneHCID 71236616—

Reaction Steps

The title compound or its salt was prepared by a procedure similar to that described for E2 starting from (4-chloro-3-(trifluoromethyl)phenyl)methanol and 8-chloro-1-methyl-3,4-dihydro-1H-pyrimido[1,6-a]pyrimidin-6(2H)-one.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09273054B2
Source datasetuspto-grants-2016_03
ORD IDord-7bd88db1de6e4369bb2e1df6016131f1
Source noteuspto-grants-2016_03