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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 920400Generated: October 26, 2026

2-(2,4-Difluorophenyl)ethanol → 8-[2-(2,4-Difluoro-phenyl)-ethoxy]-1-methyl-1,2,3,4-tetrahydro-pyrimido[1,6-a]pyrimidin-6-one

https://huagongshe.com/reaction/920400

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-(2,4-Difluorophenyl)ethanolHCID 53403461—
Reactant8-Chloro-1-methyl-3,4-dihydro-1H-pyrimido[1,6-A]pyrimidin-6(2H)-oneHCID 71743471—
Product8-[2-(2,4-Difluoro-phenyl)-ethoxy]-1-methyl-1,2,3,4-tetrahydro-pyrimido[1,6-a]pyrimidin-6-oneHCID 71236570—

Reaction Steps

The title compound or its salt was prepared by a procedure similar to that described for E11 starting from 2-(2,4-difluorophenyl)ethanol and 8-chloro-1-methyl-3,4-dihydro-1H-pyrimido[1,6-a]pyrimidin-6(2H)-one.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09273054B2
Source datasetuspto-grants-2016_03
ORD IDord-a09fcb2d982247d7a5c2a5b6be50df3e
Source noteuspto-grants-2016_03