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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 920418Generated: November 1, 2026

(4-Chloro-3-fluorophenyl)methanamine → 8-(4-Chloro-3-fluoro-benzylamino)-1-methyl-1,2,3,4-tetrahydro-pyrimido[1,6-a]pyrimidin-6-one

https://huagongshe.com/reaction/920418

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(4-Chloro-3-fluorophenyl)methanamineHCID 2757541—
Reactant8-Chloro-1-methyl-3,4-dihydro-1H-pyrimido[1,6-A]pyrimidin-6(2H)-oneHCID 71743471—
Product8-(4-Chloro-3-fluoro-benzylamino)-1-methyl-1,2,3,4-tetrahydro-pyrimido[1,6-a]pyrimidin-6-oneHCID 71236830—

Reaction Steps

The title compound or its salt was prepared by a procedure similar to that described for E59 starting from (4-chloro-3-fluorophenyl)methanamine and 8-chloro-1-methyl-3,4-dihydro-1H-pyrimido[1,6-a]pyrimidin-6(2H)-one.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09273054B2
Source datasetuspto-grants-2016_03
ORD IDord-f8b617d3fe6449fbb45dbb04e4d39fa4
Source noteuspto-grants-2016_03