HuagongsheHuagongshe Chemistry Print Report · For research reference only
8-Chloro-1-methyl-3,4-dihydro-1H-pyrimido[1,6-A]pyrimidin-6(2H)-one → 8-((4-((6-chloropyridin-3-yl)oxy)-3-fluorobenzyl)oxy)-1-methyl-3,4-dihydro-1H-pyrimido[1,6-a]pyrimidin-6(2H)-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 8-Chloro-1-methyl-3,4-dihydro-1H-pyrimido[1,6-A]pyrimidin-6(2H)-one | HCID 71743471 | — |
| Reactant | (4-((6-Chloropyridin-3-yl)oxy)-3-fluorophenyl)methanol | HCID 86676396 | — |
| Product | 8-((4-((6-chloropyridin-3-yl)oxy)-3-fluorobenzyl)oxy)-1-methyl-3,4-dihydro-1H-pyrimido[1,6-a]pyrimidin-6(2H)-one | HCID 86676395 | — |
Reaction Steps
The title compound or its salt was prepared by a procedure similar to that described for E2 starting from (4-((6-chloropyridin-3-yl)oxy)-3-fluorophenyl)methanol and 8-chloro-1-methyl-3,4-dihydro-1H-pyrimido[1,6-a]pyrimidin-6(2H)-one.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09273054B2 |
| Source dataset | uspto-grants-2016_03 |
| ORD ID | ord-9566fee4217544e7abb168fc0b438111 |
| Source note | uspto-grants-2016_03 |