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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 920442Generated: October 30, 2026

2-(4-(4-Chloro-3-fluorophenoxy)-3-fluorophenyl)ethanol → 8-(4-(4-chloro-3-fluorophenoxy)-3-fluorophenethoxy)-1-methyl-3,4-dihydro-1H-pyrimido[1,6-a]pyrimidin-6(2H)-one

https://huagongshe.com/reaction/920442

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-(4-(4-Chloro-3-fluorophenoxy)-3-fluorophenyl)ethanolHCID 71236573—
Reactant8-Chloro-1-methyl-3,4-dihydro-1H-pyrimido[1,6-A]pyrimidin-6(2H)-oneHCID 71743471—
Product8-(4-(4-chloro-3-fluorophenoxy)-3-fluorophenethoxy)-1-methyl-3,4-dihydro-1H-pyrimido[1,6-a]pyrimidin-6(2H)-oneHCID 71236689—

Reaction Steps

The title compound or its salt was prepared by a procedure similar to that described for E2 starting from 2-(4-(4-chloro-3-fluorophenoxy)-3-fluorophenyl)ethanol and 8-chloro-1-methyl-3,4-dihydro-1H-pyrimido[1,6-a]pyrimidin-6(2H)-one.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09273054B2
Source datasetuspto-grants-2016_03
ORD IDord-0fd8681330da49de9ce7d85720a030a1
Source noteuspto-grants-2016_03