Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 921334Generated: October 30, 2026

2,6-Dimethoxypyridin-3-amine → 5-chloro-N2-[6-(dimethylphosphoryl)-2-methoxypyridin-3-yl]-N4-[4-(dimethylphosphoryl)phenyl]pyrimidine-2,4-diamine

https://huagongshe.com/reaction/921334

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2,6-Dimethoxypyridin-3-amineHCID 593005—
Reactant2,5-dichloro-N-[4-(dimethylphosphoryl)phenyl]pyrimidin-4-amineHCID 86668790—
Product5-chloro-N2-[6-(dimethylphosphoryl)-2-methoxypyridin-3-yl]-N4-[4-(dimethylphosphoryl)phenyl]pyrimidine-2,4-diamineHCID 86668797—

Reaction Steps

This compound can be prepared as in Example 32 by reacting 2,5-dichloro-N-[4-(dimethylphosphoryl)phenyl]pyrimidin-4-amine with 2,6-Dimethoxypyridin-3-amine.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09273077B2
Source datasetuspto-grants-2016_03
ORD IDord-fb6f1f8c20264d79a27e6fc93e4e617c
Source noteuspto-grants-2016_03