反应详情

To a solution of 1-Amino-2-(isopropylsulphonyl)benzene (350 mg, 1.6 mmol) and 3,5,6-trichloro-1,2,4-triazine (1.6 mmol) in CH2Cl2, is added triethylamine (2 mmol). The reaction mixture is allowed to cool to room temperature, dissolved in dichloromethane and washed with an aqueous solution of Na2CO3. The dichloromethane extract is dried over MgSO4 and evaporated. The crude product is purified by Prep-HPLC.

1. washwashed with an aqueous solution of Na2CO3
2. extractionThe dichloromethane extract
3. dry with materialis dried over MgSO4
4. customevaporated
5. customThe crude product is purified by Prep-HPLC