HuagongsheHuagongshe Chemistry Print Report · For research reference only
Triphenylphosphine → HCID 86685025, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Triphenylphosphine | HCID 11776 | — |
| Reactant | tert-butyl N-(3-bromopropyl)carbamate | HCID 4460490 | — |
| Solvent | Acetonitrile | HCID 6342 | — |
| Product | HCID 86685025 | HCID 86685025 | 64% |
Reaction Steps
A mixture of tert-butyl (3-bromopropyl)carbamate (5.45 g, 22.88 mmol) and triphenylphosphine (6.0 g, 22.88 mmol) in 100 ml of acetonitrile was heated to reflux for 2 days. Upon cooling to room temperature, the compound was purified with silica chromatography using methylene chloride/methanol as an eluent to give a yield of 64% (6.15 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09273343B2 |
| Source dataset | uspto-grants-2016_03 |
| ORD ID | ord-87df036d0e9c48c68d38b19519fada87 |
| Source note | uspto-grants-2016_03 |