反应详情

A mixture of tert-butyl (3-bromopropyl)carbamate (5.45 g, 22.88 mmol) and triphenylphosphine (6.0 g, 22.88 mmol) in 100 ml of acetonitrile was heated to reflux for 2 days. Upon cooling to room temperature, the compound was purified with silica chromatography using methylene chloride/methanol as an eluent to give a yield of 64% (6.15 g).

1. temperaturewas heated
2. temperatureto reflux for 2 days
3. customthe compound was purified with silica chromatography
4. customto give a yield of 64% (6.15 g)