Silane, tris(1-methylethyl)- → HCID 178419277, compound

HRID 921513Notes

Reaction equation

HRID 921513 reaction equation
C([SiH](C(C)C)C(C)C)(C)C.[Br-:11].C(OC([NH:19][CH2:20][CH2:21][CH2:22][P+:23]([C:36]1[CH:41]=[CH:40][CH:39]=[CH:38][CH:37]=1)([C:30]1[CH:35]=[CH:34][CH:33]=[CH:32][CH:31]=1)[C:24]1[CH:29]=[CH:28][CH:27]=[CH:26][CH:25]=1)=O)(C)(C)C>C(O)(C(F)(F)F)=O.C(Cl)Cl>[Br-:11].[NH3+:19][CH2:20][CH2:21][CH2:22][P+:23]([C:36]1[CH:41]=[CH:40][CH:39]=[CH:38][CH:37]=1)([C:24]1[CH:25]=[CH:26][CH:27]=[CH:28][CH:29]=1)[C:30]1[CH:35]=[CH:34][CH:33]=[CH:32][CH:31]=1.[Br-:11]

Participants

4

Reactant 2

HCID 138754Silane, tris(1-methylethyl)-HCID 86685025HCID 86685025, compound

Product 1

HCID 178419277HCID 178419277, compound

Reagents, catalysts & solvents 1

HCID 21863450Trifluoroacetic acid methylene chlorideSolvent

Procedure

The solution of TFA/CH2Cl2 (1:1, 50 ml) containing triisoproylsilane (0.2 ml) was added to (3-((tert-butoxycarbonyl)amino) propyl)triphenylphosphonium bromide (6.15 g, 14.6 mmol). The mixture was stirred for 2 hours. After removal of the solvent, the compound was dried over vacuum and directly used in next step.

Workup

  1. customAfter removal of the solvent
  2. customthe compound was dried over vacuum

Sources & evidence

ORD record
ord-61893a2533b445968313a839c50402eb
Source dataset
uspto-grants-2016_03
Patent number
US09273343B2

Reaction notes

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