Hydrogen Bromide → 5-[2-(4-Chloro-3-fluorophenyl)piperidin-4-yl]-1,2-oxazol-3-one

HRID 92156Notes

Reaction equation

HRID 92156 reaction equation
[BrH:25].[Cl:1][c:2]1[c:3]([F:24])[cH:4][c:5]([CH:8]2[N:9]([C:20]([O:21][CH3:22])=[O:23])[CH2:10][CH2:11][CH:12]([c:14]3[cH:15][c:16](=[O:19])[nH:17][o:18]3)[CH2:13]2)[cH:6][cH:7]1>>[Cl:1][c:2]1[c:3]([F:24])[cH:4][c:5]([CH:8]2[NH:9][CH2:10][CH2:11][CH:12]([c:14]3[cH:15][c:16](=[O:19])[nH:17][o:18]3)[CH2:13]2)[cH:6][cH:7]1

Participants

3

Reactant 2

HCID 260Hydrogen BromideHCID 66731678Methyl 2-(4-chloro-3-fluorophenyl)-4-(3-oxo-1,2-oxazol-5-yl)piperidine-1-carboxylate

Product 1

HCID 667323615-[2-(4-Chloro-3-fluorophenyl)piperidin-4-yl]-1,2-oxazol-3-one

Sources & evidence

ORD record
ord-8389b92d87434d2c9607f35679ac0add
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

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