Trifluoroacetic acid → N-[5-(5-amino-2-chloro-4-fluorophenoxy)[1,3]thiazolo[5,4-b]pyridin-2-yl]cyclopropanecarboxamide
Reaction equation
[C:1]([N:5]([C:2](=[O:3])[O-:4])[c:9]1[c:10]([F:32])[cH:11][c:12]([Cl:31])[c:13]([O:15][c:16]2[cH:17][cH:18][c:19]3[c:20]([n:21]2)[s:22][c:23]([NH:25][C:26](=[O:27])[CH:28]2[CH2:29][CH2:30]2)[n:24]3)[cH:14]1)([CH3:6])([CH3:7])[CH3:8].[OH:33][C:34]([C:35]([F:36])([F:37])[F:38])=[O:39]>>[NH2:5][c:9]1[c:10]([F:32])[cH:11][c:12]([Cl:31])[c:13]([O:15][c:16]2[cH:17][cH:18][c:19]3[c:20]([n:21]2)[s:22][c:23]([NH:25][C:26](=[O:27])[CH:28]2[CH2:29][CH2:30]2)[n:24]3)[cH:14]1Participants
3
Sources & evidence
- ORD record
- ord-1998797e66574e318cd662066af2b1cd
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
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