HuagongsheHuagongshe Chemistry Print Report · For research reference only
tert-Butyl 2,7-diazaspiro[3.5]nonane-2-carboxylate → 2-((2-Chloro-5-cyano-3-(2,7-diazaspiro[3.5]nonan-7-yl)phenyl)amino)-4-(cyclopropylamino)imidazo[2,1-f][1,2,4]triazine-7-carbonitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | tert-Butyl 2,7-diazaspiro[3.5]nonane-2-carboxylate | HCID 23282935 | — |
| Reactant | 2-((2-Chloro-5-cyano-3-(piperazin-1-yl)phenyl)amino)-4-(cyclopropyl(4-methoxybenzyl)amino)imidazo[2,1-f][1,2,4]triazine-7-carbonitrile | HCID 86708492 | — |
| Product | 2-((2-Chloro-5-cyano-3-(2,7-diazaspiro[3.5]nonan-7-yl)phenyl)amino)-4-(cyclopropylamino)imidazo[2,1-f][1,2,4]triazine-7-carbonitrile | HCID 89922418 | — |
Reaction Steps
The title compound was prepared from tert-butyl 2,7-diazaspiro[3.5]nonane-2-carboxylate using a method to prepare Intermediate 11 and method analogous to that used to prepare Example 1.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09273057B2 |
| Source dataset | uspto-grants-2016_03 |
| ORD ID | ord-6f63c24d56084bb59815d5ecc8d45a3b |
| Source note | uspto-grants-2016_03 |