反应详情

5-Methoxy-1H-indole-2-carboxylic acid (4-acetyl-phenyl)-amide, made from 5-Methoxy-1H-indole-2-carboxylic acid and 4-acetyl phenylamine, and N-hydroxy-N′-aminoguanidine PTSA salt, prepared by following method discussed in Tai, et al. (J. Med. Chem. (1983) 26:1326-1329) were combined according to synthetic scheme, to obtain the pure product after purification by reverse phase HPLC: tR 20.5 min (20-60% CH3CN in H2O, 25 min); MS (m/z) 381 (MH+).

1. customprepared
2. customto obtain the pure product
3. customafter purification by reverse phase HPLC: tR 20.5 min (20-60% CH3CN in H2O, 25 min)