HuagongsheHuagongshe Chemistry Print Report · For research reference only
p-Aminoacetophenone → HCID 178488089, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | p-Aminoacetophenone | HCID 7468 | — |
| Reactant | 5-Methoxyindole-2-carboxylic acid | HCID 20401 | — |
| Reactant | 5-Methoxy-1h-indole-2-carboxylic acid (4-acetyl-phenyl)-amide | HCID 91155385 | — |
| Reactant | HCID 178427660 | HCID 178427660 | — |
| Product | HCID 178488089 | HCID 178488089 | — |
Reaction Steps
5-Methoxy-1H-indole-2-carboxylic acid (4-acetyl-phenyl)-amide, made from 5-Methoxy-1H-indole-2-carboxylic acid and 4-acetyl phenylamine, and N-hydroxy-N′-aminoguanidine PTSA salt, prepared by following method discussed in Tai, et al. (J. Med. Chem. (1983) 26:1326-1329) were combined according to synthetic scheme, to obtain the pure product after purification by reverse phase HPLC: tR 20.5 min (20-60% CH3CN in H2O, 25 min); MS (m/z) 381 (MH+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09278089B2 |
| Source dataset | uspto-grants-2016_03 |
| ORD ID | ord-8f9ccdf377b84b70bf06f2965a7f0731 |
| Source note | uspto-grants-2016_03 |