HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl 2-(4-hydroxyphenyl)cyclopropane-1-carboxylate → 2-[4-[[4-[(2Z)-2-(4-cyanophenyl)-2-methoxyiminoethoxy]phenyl]methoxy]phenyl]cyclopropane-1-carboxylic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl 2-(4-hydroxyphenyl)cyclopropane-1-carboxylate | HCID 53374426 | — |
| Reactant | 4-[(Z)-C-[[4-(bromomethyl)phenoxy]methyl]-N-methoxycarbonimidoyl]benzonitrile | HCID 88581706 | — |
| Product | 2-[4-[[4-[(2Z)-2-(4-cyanophenyl)-2-methoxyiminoethoxy]phenyl]methoxy]phenyl]cyclopropane-1-carboxylic acid | HCID 56640277 | — |
Reaction Steps
Compound 45 was prepared from ethyl 2-(4-hydroxyphenyl)cyclopropanecarboxylate (0.1 g, 0.48 mmol), and 4-{(1Z)-2-[4-(bromomethyl) phenoxy]-N-methoxyethanimidoyl}benzonitrile (0.175 g, 0.48 mmol) by following the procedure described in scheme 17.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09278915B2 |
| Source dataset | uspto-grants-2016_03 |
| ORD ID | ord-bc6f29332dc746a899f67042bc4f773f |
| Source note | uspto-grants-2016_03 |