Sodium Hydroxide → sodium 3-cyano-3-[4-[[4-[(2Z)-2-(3-fluorophenyl)-2-methoxyiminoethoxy]phenyl]methoxy]phenyl]propanoate

Participants

Role	Name	HCID	Charge
Reactant	Sodium Hydroxide	HCID 14798	—
Reactant	3-cyano-3-[4-[[4-[(2Z)-2-(3-fluorophenyl)-2-methoxyiminoethoxy]phenyl]methoxy]phenyl]propanoic acid	HCID 56640141	—
Product	sodium 3-cyano-3-[4-[[4-[(2Z)-2-(3-fluorophenyl)-2-methoxyiminoethoxy]phenyl]methoxy]phenyl]propanoate	HCID 89790380	71.59%

Reaction Steps

Compound 55 was synthesized from 3-cyano-3-{4-[(4-{[(2Z)-2-(3-fluorophenyl)-2-(methoxyimino)ethyl]oxy}benzyl)oxy]phenyl}propanoic acid (0.55 g, 1.2 mmol) and sodium hydroxide (0.092 g, 2.3 mmol) by following the procedure described in scheme 12 (0.4 g, yield: 71.59%); Purity: 96.74%.

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US09278915B2
Source dataset	uspto-grants-2016_03
ORD ID	ord-73b85e1a6bc1482dbc8a3d2ccd6b70c4
Source note	uspto-grants-2016_03