HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Hydroxide → sodium 2-[4-[[4-[(2Z)-2-methoxyimino-2-(4-methoxyphenyl)ethoxy]phenyl]methoxy]phenyl]cyclopropane-1-carboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | 2-[4-[[4-[(2Z)-2-methoxyimino-2-(4-methoxyphenyl)ethoxy]phenyl]methoxy]phenyl]cyclopropane-1-carboxylic acid | HCID 56640278 | — |
| Product | sodium 2-[4-[[4-[(2Z)-2-methoxyimino-2-(4-methoxyphenyl)ethoxy]phenyl]methoxy]phenyl]cyclopropane-1-carboxylate | HCID 87111469 | 27.84% |
Reaction Steps
Compound 57 was synthesized from 2-{4-[(4-{[(2Z)-2-(methoxyimino)-2-(4-methoxyphenyl)ethyl]oxy}benzyl)oxy]phenyl}cyclopropanecarboxylic acid (0.08 g, 0.2 mmol) and sodium hydroxide (0.013 g, 0.3 mmol) by following the procedure described in scheme 12 (0.022 g, yield: 27.84%); Purity: 98.61%.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09278915B2 |
| Source dataset | uspto-grants-2016_03 |
| ORD ID | ord-0830c71004584692ab51e513c44d8adc |
| Source note | uspto-grants-2016_03 |