Hydrochloric Acid → Ethyl 6-(tert-butoxycarbonyl(2,6-difluorophenyl)amino)-2-(2,4-difluorophenyl)nicotinate
Reaction equation
[C:37](=[O:38])([O-:39])[O-:40].[CH3:44][S:45]([CH3:46])=[O:47].[Cl:1][c:2]1[n:3][c:4](-[c:13]2[c:14]([F:20])[cH:15][c:16]([F:19])[cH:17][cH:18]2)[c:5]([C:6](=[O:7])[O:8][CH2:9][CH3:10])[cH:11][cH:12]1.[ClH:43].[Cs+:41].[Cs+:42].[F:21][c:22]1[c:23]([NH:29][C:30]([O:31][C:32]([CH3:33])([CH3:34])[CH3:35])=[O:36])[c:24]([F:28])[cH:25][cH:26][cH:27]1>>[c:2]1([N:29]([c:23]2[c:22]([F:21])[cH:27][cH:26][cH:25][c:24]2[F:28])[C:30]([O:31][C:32]([CH3:33])([CH3:34])[CH3:35])=[O:36])[n:3][c:4](-[c:13]2[c:14]([F:20])[cH:15][c:16]([F:19])[cH:17][cH:18]2)[c:5]([C:6](=[O:7])[O:8][CH2:9][CH3:10])[cH:11][cH:12]1Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-a1aaca39977c4a87bfe7d99abae1c403
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
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