HCID 59760132, compound → HCID 23136325, compound

Participants

Reaction Steps

To a 500 mL parr shaker flask was charged with Ethyl (2E)-3-(2,5-difluoro-4-methoxyphenyl)prop-2-enoate (0.1 g, 0.41 mmol), ethyl acetate (5 mL). To the reaction mixture was added 10% Pd—C (20%) and kept for hydrogenation using bladder 1 h. After completion of the reaction, the reaction mixture was filtered through celite, washed thoroughly with ethyl acetate (20 mL) and concentrated to distill off the solvent. The product was obtained as brown solid (0.080 g, yield: 80.0%).

Provenance & Evidence