反应详情

To a 50 mL RB flask fitted with magnetic stirrer were charged ethyl acetate (15 mL), to that stirred solvent was added methyl 3-[4-(benzyloxy)phenyl]-3-oxopropanoate (0.3 g, 1.05 mmol), and palladium carbon 10% (80 mg) was added. After addition, the hydrogen balloon was fixed to the reaction mixture and stirred at room temperature for 1 h. After 3 h, the reaction mixture was filtered through celite. Then the organic layer was concentrated and dried. The product was obtained as colourless liquid (0.2 g, Yield: 98%).

1. customTo a 50 mL RB flask fitted with magnetic stirrer
2. additionwas added
3. additionAfter addition
4. stirringstirred at room temperature for 1 h
5. filtrationthe reaction mixture was filtered through celite
6. concentrationThen the organic layer was concentrated
7. customdried