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HRID922428

反应详情

EQUATION

反应方程式

HRID 922428 的结构方程式

REACTANTS

反应物

2
结构：CC(C)(C)OC(=O)N1CCO[C@@H](C(=O)O)C1
HCID6559076

(2R)-4-(tert-Butoxycarbonyl)morpholine-2-carboxylic acid

C10H17NO5

结构：COC(=O)NCC#Cc1cc(C(C)NC2CC2)cnc1OC
HCID89939691

未命名化合物

PRODUCTS

生成物

1
结构：COC(=O)NCC#Cc1cc(C(C)N(C(=O)[C@H]2CN(C(=O)OC(C)(C)C)CCO2)C2CC2)cnc1OC
HCID89939690

未命名化合物

PROCEDURE

实验过程

Methyl (3-{5-[1-(cyclopropylamino)ethyl]-2-methoxypyridin-3-yl}prop-2-yn-1-yl)carbamate and (2R)-4-(tert-butoxycarbonyl)morpholine-2-carboxylic acid were treated in the similar manner to Example 162 to give tert-butyl (2R)-2-({cyclopropyl[1-(6-methoxy-5-{3-[(methoxycarbonyl)amino]prop-1-yn-1-yl}pyridin-3-yl)ethyl]amino}carbonyl)morpholine-4-carboxylate [Ex(296-4)] as a colorless oil.