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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 922562Generated: October 31, 2026

Potassium Carbonate → HCID 89654198, compound

https://huagongshe.com/reaction/922562

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPotassium CarbonateHCID 11430—
Reactant2-Bromo-5-hydroxypyridineHCID 2762865—
ReactantHCID 117696598HCID 117696598—
SolventAcetonitrileHCID 6342—
ProductHCID 89654198HCID 89654198—

Reaction Conditions

Temperature70 °C

Reaction Steps

The mixture of 0.30 g (1.7 mmol) of 2-bromo-5-hydroxypyridine, 0.59 g (3.5 mmol) of 1-bromoethyl-2,2-difluorocyclopropane and 0.60 g (4.3 mmol) of K2CO3 in 10 ml ACN is stirred at 70° C. over night. The reaction mixture is filtered over alumina/activated carbon. The solvent is removed in vacuo.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09278954B2
Source datasetuspto-grants-2016_03
ORD IDord-d0f2de82ac274f11b144b6d892f93f6b
Source noteuspto-grants-2016_03