Acetonitrile → HCID 70982804, compound

HRID 922629Notes

Reaction equation

HRID 922629 reaction equation
[Cl:1][C:2]1[N:3]=[CH:4][NH:5][C:6]=1[Cl:7].[OH-].[K+].BrCC[C:13]1[C:22]2[C:17](=[CH:18][CH:19]=[CH:20][CH:21]=2)[CH:16]=[CH:15][CH:14]=1.[C:23](#N)[CH3:24]>>[CH2:23]([C:15]1[CH:14]=[CH:13][C:22]2[C:17](=[CH:18][CH:19]=[CH:20][CH:21]=2)[C:16]=1[N:3]1[C:2]([Cl:1])=[C:6]([Cl:7])[N:5]=[CH:4]1)[CH3:24]

Participants

5

Reactant 4

HCID 6342AcetonitrileHCID 14797Potassium HydroxideHCID 1395411-(2-Bromoethyl)naphthaleneHCID 1400184,5-Dichloroimidazole

Product 1

HCID 70982804HCID 70982804, compound

Procedure

4,5-Dichloroimidazole (1 mmol) will be dissolved into 1 mL of acetonitrile. Potassium hydroxide (0.061 g, 1.1 mmol) will be added and the mixture will be allowed to stir for 0.5 h. 2-bromoethylnaphthalene (1 mmol) will be added and the solution will be allowed to reflux overnight. The solution will be filtered hot to remove a white precipitate (presumed to be KBr) and the solution will be allowed to cool to room temperature. The volatiles will be removed en vacuo resulting in the product.

Workup

  1. temperatureto reflux overnight
  2. filtrationThe solution will be filtered hot
  3. customto remove a white precipitate (presumed to be KBr)
  4. customThe volatiles will be removed en vacuo
  5. customresulting in the product

Sources & evidence

ORD record
ord-9e40f8d775834cd593e56ee73978f895
Source dataset
uspto-grants-2016_03
Patent number
US09278951B2

Reaction notes

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