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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 922973Generated: October 30, 2026

5-Amino-2-chloropyridine → HCID 58614676, compound

https://huagongshe.com/reaction/922973

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-Amino-2-chloropyridineHCID 79305—
Reactant3-Chloro-4-(4-chloro-3-(pyridin-2-yl)phenylcarbamoyl)benzoic acidHCID 66878605—
ProductHCID 58614676HCID 58614676—

Reaction Steps

50 mg of 3-chloro-4-(4-chloro-3-(pyridin-2-yl)phenylcarbamoyl)benzoic acid was coupled to 6-chloropyridin-3-amine via Procedure G. The crude product was purified on reverse phase HPLC to yield 2-chloro-N1-(4-chloro-3-(pyridin-2-yl)phenyl)-N4-(6-chloropyridin-3-yl)terephthalamide. MS (Q1) 497 (M)+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09278961B2
Source datasetuspto-grants-2016_03
ORD IDord-cc1620fcdc0c40a789173447a449a326
Source noteuspto-grants-2016_03