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HRID923008

反应详情

EQUATION

反应方程式

HRID 923008 的结构方程式

REACTANTS

反应物

2
结构：CS(=O)(=O)Cc1cccc(C(=O)O)c1
HCID4962583

未命名化合物

结构：Nc1ccc(Cl)c(-c2ccccn2)c1
HCID40151925

4-Chloro-3-(pyridin-2-yl)aniline

C11H9ClN2

PRODUCTS

生成物

1
结构：CS(=O)(=O)Cc1cccc(C(=O)Nc2ccc(Cl)c(-c3ccccn3)c2)c1
HCID58614934

未命名化合物

PROCEDURE

实验过程

300 mg of methyl 3-(bromomethyl)benzoate was reacted via Procedure O to give methyl 3-(methylsulfonylmethyl)benzoate. 230 mg of methyl 3-(methylsulfonylmethyl)benzoate was reacted via Procedure M to give 3-(methylsulfonylmethyl)benzoic acid. 75 mg of 4-chloro-3-(pyridin-2-yl)aniline was coupled to 3-(methylsulfonylmethyl)benzoic acid via Procedure G. The crude product was purified by reverse phase HPLC to yield pure N-(4-chloro-3-(pyridin-2-yl)phenyl)-3-(methylsulfonylmethyl)benzamide. MS (Q1) 401 (M)+.

WORKUP

后处理

  1. customThe crude product was purified by reverse phase HPLC