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HRID923044

反应详情

EQUATION

反应方程式

HRID 923044 的结构方程式

REACTANTS

反应物

3
结构：CS(=O)(=O)Nc1ccc(C(=O)O)c(Cl)c1
HCID18350497

未命名化合物

结构：Nc1ccc(Cl)c(-c2ccccn2)c1
HCID40151925

4-Chloro-3-(pyridin-2-yl)aniline

C11H9ClN2

结构：COC(=O)c1ccc(NS(C)(=O)=O)cc1Cl
HCID54238017

未命名化合物

PRODUCTS

生成物

1
结构：CS(=O)(=O)Nc1ccc(C(=O)Nc2ccc(Cl)c(-c3ccccn3)c2)c(Cl)c1
HCID52948347

未命名化合物

PROCEDURE

实验过程

4.2 g of methyl 2-chloro-4-(methylsulfonamido)benzoate was hydrolyzed via Procedure M. 1 g of 4-chloro-3-(pyridin-2-yl)aniline was coupled to 1.35 g of 2-chloro-4-(methylsulfonamido)benzoic acid via Procedure G. The crude product was purified by reverse phase HPLC to yield 2-chloro-N-(4-chloro-3-(pyridin-2-yl)phenyl)-4-(methylsulfonamido)benzamide. MS (Q1) 436.1 (M)+.

WORKUP

后处理

  1. customThe crude product was purified by reverse phase HPLC