HCID 178513171, compound → 3-(3,4-dichlorophenyl)-1H-1,2,4-triazol-5-amine

HRID 923327Notes

Reaction equation

HRID 923327 reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]([CH:12]=[CH:13][C:14]=1[Cl:15])[C:5]([NH:7][NH:8][C:9](=[NH:11])[NH2:10])=O>O>[Cl:1][C:2]1[CH:3]=[C:4]([C:5]2[N:10]=[C:9]([NH2:11])[NH:8][N:7]=2)[CH:12]=[CH:13][C:14]=1[Cl:15]

Participants

3

Reactant 1

HCID 178513171HCID 178513171, compound

Product 1

HCID 1785082943-(3,4-dichlorophenyl)-1H-1,2,4-triazol-5-amineYield 89.3%

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

A solution of 2-(3,4-dichlorobenzoyl)hydrazinecarboximidamide (9.5 g, 38.62 mmol) in water (150 ml) was stirred for 7 h at reflux. The solids were collected by filtration to afford 3-(3,4-dichlorophenyl)-1H-1,2,4-triazol-5-amine as an off-white solid (7.9 g, 89%).

Workup

  1. temperatureat reflux
  2. filtrationThe solids were collected by filtration

Sources & evidence

ORD record
ord-e9a07252ac00405191c3eb46ce821ad7
Source dataset
uspto-grants-2016_03
Patent number
US09278973B2

Reaction notes

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