4-Chlorobenzoic Acid → 4-Chlorobenzoyl chloride

HRID 923337Notes

Reaction equation

HRID 923337 reaction equation
[Cl:1][C:2]1[CH:10]=[CH:9][C:5]([C:6](O)=[O:7])=[CH:4][CH:3]=1.S(Cl)([Cl:13])=O>>[Cl:1][C:2]1[CH:10]=[CH:9][C:5]([C:6]([Cl:13])=[O:7])=[CH:4][CH:3]=1

Participants

3

Reactant 2

HCID 63184-Chlorobenzoic AcidHCID 24386Thionyl Chloride

Product 1

HCID 85014-Chlorobenzoyl chloride

Procedure

The solution of 4-chlorobenzoic acid (5 g, 31.94 mmol) in thionyl chloride (150 ml) was stirred for 5 h at 80° C. and then concentrated under vacuum to give 4-chlorobenzoyl chloride as a brown oil (4.5 g, crude).

Workup

  1. concentrationconcentrated under vacuum

Sources & evidence

ORD record
ord-691694f5115b44ea932318cd63a89a62
Source dataset
uspto-grants-2016_03
Patent number
US09278973B2

Reaction notes

Loading…