HCID 178424296, compound → HCID 178424211, compound

HRID 923354Notes

Reaction equation

HRID 923354 reaction equation
[CH3:1][C:2]1[CH:14]=[CH:13][CH:12]=[CH:11][C:3]=1[C:4]([NH:6][NH:7][C:8](=[NH:10])[NH2:9])=O>O>[C:2]1([CH3:1])[CH:14]=[CH:13][CH:12]=[CH:11][C:3]=1[C:4]1[N:9]=[C:8]([NH2:10])[NH:7][N:6]=1

Participants

3

Reactant 1

HCID 178424296HCID 178424296, compound

Product 1

HCID 178424211HCID 178424211, compoundYield 66.2%

Reagents, catalysts & solvents 1

HCID 962WaterSolvent2×

Procedure

A solution of 2-(2-methylbenzoyl)hydrazinecarboximidamide (5 g) in water (40 mL) was stirred overnight at 100° C. The reaction mixture was diluted with H2O (20 mL) and the solid was collected by filtration and washed with water (20 mL) to afford 3-o-tolyl-1H-1,2,4-triazol-5-amine (3 g, 66% yield) as a white solid.

Workup

  1. filtrationthe solid was collected by filtration
  2. washwashed with water (20 mL)

Sources & evidence

ORD record
ord-d368608fad6d4ec8b65788fc510db9ee
Source dataset
uspto-grants-2016_03
Patent number
US09278973B2

Reaction notes

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