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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 923633Generated: October 30, 2026

Sulfuric Acid → Pyridinoisothiazolone

https://huagongshe.com/reaction/923633

Reaction equation

Participants

RoleNameHCIDCharge
ReactantSulfuric AcidHCID 1118—
ReactantHCID 178425247HCID 178425247—
ReactantHCID 178425618HCID 178425618—
ProductPyridinoisothiazoloneHCID 57790288—

Reaction Steps

treating 2-mercapto-6-methylnicotinonitrile and 2-mercapto-4,6-dimethylnicotinonitrile in concentrated H2SO4 at 100° C. to give pyridinoisothiazolone compounds 3 (R1═H, R2=Me) and 4 (R1═R2=Me), respectively;

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09278982B2
Source datasetuspto-grants-2016_03
ORD IDord-f3d5fd9daa784428bff1da7a6cb278e0
Source noteuspto-grants-2016_03