HuagongsheHuagongshe Chemistry Print Report · For research reference only
Morpholine → HCID 67951154, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Morpholine | HCID 8083 | — |
| Reactant | 1-Ethyl-3-(3'-dimethylaminopropyl)carbodiimide | HCID 15908 | — |
| Reactant | Diisopropylethylamine | HCID 81531 | — |
| Reactant | HCID 67951152 | HCID 67951152 | — |
| Catalyst | 4-(Dimethylamino)pyridine | HCID 14284 | — |
| Product | HCID 67951154 | HCID 67951154 | 82% |
Reaction Steps
Alternatively, the coupling reaction of acid 26 with morpholine in the presence of EDCI, DMAP and DIEA, by a procedure similar to that for compound 21 (YMU1), gave compound 27 in 82% yield.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09278982B2 |
| Source dataset | uspto-grants-2016_03 |
| ORD ID | ord-18e5598de85940bda1710ee2485c3bbd |
| Source note | uspto-grants-2016_03 |