(S)-(-)-N-Boc-prolinol → 185951-21-7

HRID 923706Notes

Reaction equation

HRID 923706 reaction equation
[C:1]([O:5][C:6]([N:8]1[CH2:14][C@H:13]([O:15][CH3:16])[CH2:12][C@H:9]1[CH2:10][OH:11])=[O:7])([CH3:4])([CH3:3])[CH3:2].C(OC(N1CCC[C@H]1CO)=O)(C)(C)C>>[C:1]([O:5][C:6]([N:8]1[CH2:14][C@H:13]([O:15][CH3:16])[CH2:12][C@H:9]1[CH:10]=[O:11])=[O:7])([CH3:4])([CH3:3])[CH3:2]

Participants

3

Reactant 2

HCID 643448(S)-(-)-N-Boc-prolinolHCID 20648577185951-13-7

Product 1

HCID 118193061185951-21-7

Procedure

With the exception that N-t-butoxycarbonyl-trans-4-methoxy-L-prolinol, instead of N-t-butoxycarbonyl-L-prolinol, was used, the same procedure as in Preparation Example 1-1 was repeated to afford the title compound. 40.8 g (97%).

Workup

  1. customthe same procedure as in Preparation Example 1-1

Sources & evidence

ORD record
ord-d02b4517898c4804b92eb92d574988b2
Source dataset
uspto-grants-2016_03
Patent number
US09278996B2

Reaction notes

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