HuagongsheHuagongshe Chemistry Print Report · For research reference only
(S)-(-)-N-Boc-prolinol → 185951-21-7
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (S)-(-)-N-Boc-prolinol | HCID 643448 | — |
| Reactant | (2S,4R)-tert-Butyl 2-(hydroxymethyl)-4-methoxypyrrolidine-1-carboxylate | HCID 20648577 | — |
| Product | 185951-21-7 | HCID 118193061 | — |
Reaction Steps
With the exception that N-t-butoxycarbonyl-trans-4-methoxy-L-prolinol, instead of N-t-butoxycarbonyl-L-prolinol, was used, the same procedure as in Preparation Example 1-1 was repeated to afford the title compound. 40.8 g (97%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09278996B2 |
| Source dataset | uspto-grants-2016_03 |
| ORD ID | ord-d02b4517898c4804b92eb92d574988b2 |
| Source note | uspto-grants-2016_03 |