反应详情

6,8-Bis-(4-hydroxy-but-1-ynyl)-3-(4-methoxy-phenyl)-chromen-2-one is hydrogenated in THF on Pd/activated charcoal until the reaction is completed. The catalyst is filtered off, the solvent removed in vacuo and the crude product is filtered through silica gel with THF/toluene (3:2) and recrystallized from toluene. 6,8-Bis-(4-hydroxy-butyl)-3-(4-methoxy-phenyl)-chromen-2-one is obtained as a colourless solid.

1. filtrationThe catalyst is filtered off
2. customthe solvent removed in vacuo
3. filtrationthe crude product is filtered through silica gel with THF/toluene (3:2)
4. customrecrystallized from toluene