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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 923861Generated: November 2, 2026

2-Methylpyridine-3-boronic acid → HCID 118195140, compound

https://huagongshe.com/reaction/923861

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Methylpyridine-3-boronic acidHCID 20111647—
Reactant(R)-5-bromo-6-(3-hydroxypyrrolidin-1-yl)-N-(4-(trifluoromethoxy)phenyl)nicotinamideHCID 86702593—
ProductHCID 118195140HCID 118195140—

Reaction Steps

The title compound was prepared in an analogous fashion to that described in Example 36 using (R)-5-bromo-6-(3-hydroxypyrrolidin-1-yl)-N-(4-(trifluoromethoxy)phenyl)nicotinamide (Stage 35.1) and (2-methylpyridin-3-yl)boronic acid to afford a white solid. UPLC-MS (condition 1) tR=1.71 min, m/z=459.0 [M+H]+, m/z=547.2 [M−H]−.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09278981B2
Source datasetuspto-grants-2016_03
ORD IDord-e9a35b102f614e088c8fb5cfed735104
Source noteuspto-grants-2016_03