HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Methylpyridine-3-boronic acid → HCID 118195140, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Methylpyridine-3-boronic acid | HCID 20111647 | — |
| Reactant | (R)-5-bromo-6-(3-hydroxypyrrolidin-1-yl)-N-(4-(trifluoromethoxy)phenyl)nicotinamide | HCID 86702593 | — |
| Product | HCID 118195140 | HCID 118195140 | — |
Reaction Steps
The title compound was prepared in an analogous fashion to that described in Example 36 using (R)-5-bromo-6-(3-hydroxypyrrolidin-1-yl)-N-(4-(trifluoromethoxy)phenyl)nicotinamide (Stage 35.1) and (2-methylpyridin-3-yl)boronic acid to afford a white solid. UPLC-MS (condition 1) tR=1.71 min, m/z=459.0 [M+H]+, m/z=547.2 [M−H]−.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09278981B2 |
| Source dataset | uspto-grants-2016_03 |
| ORD ID | ord-e9a35b102f614e088c8fb5cfed735104 |
| Source note | uspto-grants-2016_03 |